Heart 1997;78:550-554 ( December )
Asian Indians, coronary artery disease, and physical exercise
a Department of Medicine,
Scunthorpe General Hospital, Scunthorpe, UK, b Department of Cardiology, Wythenshawe Hospital, Manchester, UK
Correspondence to: Dr Dhawan, Consultant Cardiologist, Scunthorpe General Hospital, Cliff Gardens, Scunthorpe DN15 7BH, UK.
Accepted for publication 11 August 1997
Objective
To evaluate the relation of
physical activity to different clinical and biochemical risk factors
for coronary artery disease among people from different ethnic groups
with angiographically proven coronary artery disease.
Subjects
British Asians, Indian Asians, and white
people suffering from coronary artery disease, and their respective controls.
Interventions
History, physical examination,
coronary angiography (at baseline), laboratory investigations.
Main outcome measures
Relation of physical
activity level to serum insulin, glucose, cholesterol, triglycerides,
and high density lipoproteins, systolic and diastolic blood pressures,
and body mass index in patients and controls.
Results
391 male patients were studied, of whom
260 (66.5%) were classified as sedentary. Mean serum insulin at 0, 1, and 2 hours after 75 g oral glucose was higher among the sedentary
population (17.1 v 11.6, 88.2 v 62.1, and
57.9 v 36.2 µU/ml, respectively (all p < 0.0001).
Mean body mass index was also higher among the sedentary population
(25.53 v 23.95, p < 0.0001), as were mean serum
triglycerides (1.85 v 1.60 mmol/l, p < 0.01) and
systolic and diastolic blood pressures (133.9 v 129.4, p < 0.05, and 81.1 v 79.0, p < 0.01). There was no
difference in the mean serum cholesterol and high density lipoprotein
between the two groups. British Asians were the most sedentary and
Indian Asians the most physically active.
Conclusions
There are marked differences in the
level of physical activity among the various ethnic groups in the
United Kingdom. In each ethnic group, physical activity reduced mean
serum insulin, body mass index, and serum triglycerides and had a
favourable effect on systolic and diastolic blood pressures. Promotion
of physical activity could be of value for the Asian community in the
United Kingdom.
© 1997 by Heart
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