Heart 1998;79:50-55 ( January )
Screening for atrial fibrillation in primary care
a Cardiothoracic Unit, Northern General
Hospital, Sheffield S5 7AU,
UK, b Primary Care, Northern General
Hospital
Correspondence to: Dr Wheeldon.
Accepted for publication 3 October 1997
Objective
To investigate a population of
elderly people for atrial fibrillation and to determine how many of the
cases identified might benefit from treatment with anticoagulants.
Methods
From a practice of four primary care
physicians, 1422 patients aged 65 years and over were identified, of
whom 1207 (85% of the total population) underwent electrocardiographic
screening to detect the presence of atrial fibrillation. Patients with
the arrhythmia were further evaluated by echocardiography and
interview, to stratify their risk of stroke based on echocardiographic
and clinical risk factors, their perceived risk from
anticoagulation, and their attitude towards this treatment. Their
primary care physician was also interviewed to determine the factors
influencing the prescription of anticoagulants.
Results
The arrhythmia occurred
in 65 patients (5.4% overall), its prevalence increasing markedly with
age (2.3% in 65 to 69 years age group; 8.1% in those over 85).
Warfarin was being prescribed to 21.4% of these patients, although the
findings of the study indicate that a further 20% were eligible for
this treatment. Symptoms suggestive of cardiac failure were common
(32.1%) and coexisting pathology was often identified by cardiac
ultrasound in these patients (left ventricular hypertrophy, 32.1%;
impaired left ventricular contractility, 21.4%; left atrial
dilatation, 80.4%; mitral annular calcification, 42.9%; mitral
stenosis, 7.1%; mitral regurgitation, 48.2%; aortic stenosis, 8.9%).
In all but one case, the decision to anticoagulate was based on the
clinical rather than the echocardiographic findings.
Conclusions
Individual risk-benefit
assessment in elderly patients with atrial fibrillation suggests that
almost half (41.4%) are eligible for full anticoagulation with
warfarin, whereas presently only one fifth are receiving this
treatment. The decision to anticoagulate can be made on clinical
grounds in most cases. If these results are confirmed, a doubling of
the current number of patients taking anticoagulants can be anticipated.
© 1998 by Heart
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