Heart 1998;79:356-361 ( April )
Circumstances and causes of out-of-hospital cardiac arrest in sudden death survivors
a Department of Cardiology, University
hospital of Maastricht, PO Box 5800, 6202 AZ Maastricht, Netherlands, b Department of Pathology, University Hospital of
Maastricht, c Department of General
Practice, University of Maastricht, d District Medical and Social Health Service of
Southern Limburg, Maastricht, Netherlands.
Correspondence to: Dr de Vreede-Swagemakers.
Accepted for publication 5 January 1998
Objective
To study the circumstances and medical
profile of out-of-hospital sudden cardiac arrest (SCA) patients in whom
resuscitation was attempted by the ambulance service, and to identify
causes of SCA in survivors and factors that influence resuscitation
success rate.
Methods
During a five year period (1991-95) all
cases of out-of-hospital SCA between the ages of 20 and 75 years and
living in the Maastricht area in the Netherlands were studied.
Information was gathered about the circumstances of SCA, as well as
medical history for all patients in whom resuscitation was attempted by
the ambulance personnel. Causes of SCA in survivors were studied and
logistic regression analysis was performed to identify factors
associated with survival.
Results
Of 288 SCA patients in whom
cardiopulmonary resuscitation (CPR) and advanced life support were
applied, 47 (16%) were discharged alive from the hospital. Their mean
(SD) age was 58 (11) years, 37 (79%) were men, and 24 (51%) had a
history of cardiac disease. Acute myocardial infarction was diagnosed
in 24 (51%) of the survivors; seven with and 17 without a history of
cardiac disease. Ventricular fibrillation (VF) or ventricular
tachycardia (VT) as the first documented rhythm was significantly
positively associated with survival (odds ratio (OR) 5.7, 95%
confidence interval (CI) 2.1 to 15.9). A time interval of less than
four minutes between the moment of collapse and the start of
resuscitation, and an ambulance delay time of less than eight minutes
were significantly positively associated with survival (OR 3.3, 95% CI
1.3 to 8.6, and OR, 3.6, 95% CI 1.3 to 10.5, respectively). A history
of cardiac disease was negatively associated with survival (OR 0.46, 95% CI 0.21 to 0.98).
Conclusions
Acute myocardial infarction was the
underlying mechanism of SCA in most of the survivors, especially in
those without a history of cardiac disease. CPR within four minutes, an
ambulance delay time less than eight minutes, and VT or VF diagnosed by
the paramedics were positively associated with success.
© 1998 by Heart
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