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Heart 1998;80:377-382 ( October )
Department of Geriatric Medicine,
University of Liverpool, Liverpool, UK
Correspondence to: Dr S T O'Keeffe, Department of Geriatric Medicine, St Michael's Hospital, Dun Laoghaire, Co Dublin, Republic of Ireland.
Accepted for publication 16 February 1998
Objective
To examine the reproducibility and
responsiveness to change of a six minute walk test and a quality of
life measure in elderly patients with heart failure.
Design
Longitudinal within patient study.
Subjects
60 patients with heart failure (mean age
82 years) attending a geriatric outpatient clinic, 45 of whom underwent
a repeat assessment three to eight weeks later.
Main outcome measures
Subjects
underwent a standardised six minute walk test and completed the chronic
heart failure questionnaire (CHQ), a heart failure specific quality of
life questionnaire. Intraclass correlation coefficients (ICC) were
calculated using a random effects one way analysis of variance as a
measure of reproducibility. Guyatt's responsiveness coefficient and
effect sizes were calculated as measures of responsiveness to change.
Results
24 patients reported no major
change in cardiac status, while seven had deteriorated and 14 had
improved between the two clinic visits. Reproducibility was
satisfactory (ICC > 0.75) for the six minute walk test, for the total
CHQ score, and for the dyspnoea, fatigue, and emotion domains of the
CHQ. Effect sizes for all measures were large (> 0.8), and
responsiveness coefficients were very satisfactory (> 0.7). Effect
sizes for detecting deterioration were greater than those for detecting improvement.
Conclusions
Quality of life assessment and
a six minute walk test are reproducible and responsive measures of
cardiac status in frail, very elderly patients with heart failure.
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