Heart 1999;81:17-24 ( January )
Exercise four hour redistribution thallium-201 single photon emission computed tomography and exercise induced ST segment elevation in detecting the viable myocardium in patients with acute myocardial infarction
a First
Department of Internal Medicine, Osaka City University Medical School,
Osaka, Japan, b Division of Nuclear Medicine, Osaka City
University Medical School
Correspondence to: Dr H Yamagishi, First Department of Internal Medicine, Osaka City University Medical School, 1-5-7 Asahi-Machi, Abeno-Ku, Osaka 545-8586, Japan.
Accepted for publication 8 July 1998
Objective
To
investigate the specificity and sensitivity of the combination of
redistribution in exercise thallium-201 single photon emission computed
tomography (SPECT) and exercise induced ST elevation for detecting
the viable myocardium in patients with acute myocardial infarction.
Design37 patients
were studied within seven weeks of onset of Q wave myocardial
infarction (anterior in 22, inferior in 15). All patients underwent
exercise four hour redistribution thallium-201 SPECT and positron
emission tomography using fluorine-18-fluorodeoxyglucose (FDG) and
nitrogen-13 ammonia under fasting conditions.
ResultsSixteen
patients showed exercise induced ST elevation 
1.5 mm, and 15 of
these had increased FDG uptake in the infarct region. Eleven of 16 patients (10 of 11 patients with anterior infarctions) with
irreversible thallium-201 defects and increased FDG uptake showed
exercise induced ST elevation. The sensitivity, specificity, and
predictive accuracy of redistribution, exercise induced ST segment
elevation, or both for detecting increased FDG uptake were 82%, 75%,
and 67% (94%, 75%, and 91% for anterior infarctions), respectively.
ConclusionsIn
patients with acute Q wave myocardial infarction, the combination of
redistribution in exercise thallium-201 SPECT and exercise induced ST
elevation can detect the viable myocardium in the infarct region with
high sensitivity and specificity, especially in patients with anterior infarctions.
© 1999 by Heart
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
Hahalis, G., Stathopoulos, C., Apostolopoulos, D., Vasilakos, P., Alexopoulos, D., Manolis, A. S.
(2002). Contribution of the sT elevation/T-wave normalization in q-wave leads during routine, pre-discharge treadmill exercise test to patient management and risk stratification after acute myocardial infarction: A 2.5-year follow-up study. J Am Coll Cardiol
40: 62-70
[Abstract] [Full Text] -
BERTELLA, M, SCALISE, F, ERIANO, G, VALENTINI, R
(2000). Exercise four hour redistribution thallium-201 SPECT and exercise induced ST segment elevation in detecting viable myocardium in patients with acute MI. Heart
83: 103a-103
[Full Text] -
WALTON, S.
(1999). Radionuclide techniques for myocardial viability and hibernation. Heart
81: 6-7
[Full Text]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
