Cardiovascular medicine
Diagnosis of carotid sinus hypersensitivity in older adults:
carotid sinus massage in the upright position is essential
S W Parrya, D A Richardsona, D O'Sheaa, B Senb, R A Kennya
a Cardiovascular
Investigation Unit and Institute for the Health of the Elderly,
University of Newcastle Upon Tyne, Ward 15 Offices, Royal Victoria
Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK, b Accident and Emergency Department, Royal
Victoria Infirmary
Correspondence to: Dr Parry email: s.w.parry{at}ncl.ac.uk
Accepted 19 July 1999
OBJECTIVE
To assess the diagnostic value of
supine and upright carotid sinus massage in elderly patients.
DESIGN
Prospective controlled cohort study.
SETTING
Three inner city accident and emergency
departments and a dedicated syncope facility.
PATIENTS
1375 consecutive patients aged > 55 years
presenting with unexplained syncope and drop attacks; 25 healthy controls.
INTERVENTIONS
Bilateral supine carotid sinus massage,
repeated in the 70° head up tilt position if the initial supine test
was not diagnostic of cardioinhibitory and mixed carotid sinus hypersensitivity.
MAIN OUTCOME MEASURES
Diagnosis of cardioinhibitory or
mixed carotid sinus hypersensitivity; clinical characteristics of
supine v upright positive groups.
RESULTS
226 patients were excluded for contraindications
to carotid sinus massage. Of 1149 patients undergoing massage, 223 (19%) had cardioinhibitory or mixed carotid sinus hypersensitivity; 70 (31%) of these had a positive response to massage with head up tilt
following negative supine massage (95% confidence interval, 25.3% to
37.5%). None of the healthy controls showed carotid sinus hypersensitivity on erect or supine massage. The initially positive supine test had 74% specificity and 100% sensitivity; these were both
100% for the upright positive test. The clinical characteristics of
the supine v upright positive subgroups were similar.
CONCLUSIONS
The diagnosis of carotid sinus
hypersensitivity amenable to treatment by pacing may be missed in one
third of cases if only supine massage is performed. Massage should be
done routinely in the head up tilt position if the initial supine test
is negative.
Keywords: carotid sinus; tilt table testing; syncope; elderly patients
© 2000 by Heart
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