Interventional cardiology surgery
Limitations of the Parsonnet score for measuring risk stratified
mortality in the north west of England
K Wynne-Jonesa, M Jacksonb, G Grottec, B Bridgewatera, on
behalf of the North West Regional Cardiac Surgery Audit
Steering Group
a Departments of
Cardiothoracic Surgery and Clinical Audit, Wythenshawe Hospital,
Southmoor Road, Manchester M23 9LT, UK, b Departments of
Cardiothoracic Surgery and Clinical Audit, The Cardiothoracic
Centre-Liverpool, Thomas Drive, Liverpool L14 3PE, UK, c Department of Cardiothoracic Surgery,
Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
Correspondence to: Dr Bridgewater email: ben{at}bridgewaterb.fsnet.co.uk
Accepted 8 February
2000
OBJECTIVE
To study the use of the Parsonnet score to
predict mortality following adult cardiac surgery.
DESIGN
Prospective study.
SETTING
All centres performing adult cardiac surgery in
the north west of England.
SUBJECTS
8210 patients undergoing surgery between April
1997 and March 1999.
MAIN OUTCOME MEASURES
Risk factors and in-hospital
mortality were recorded according to agreed definitions. Ten per cent
of cases from each centre were selected at random for validation. A
Parsonnet score was derived for each patient and its predictive ability
was studied.
RESULTS
Data collection was complete. The operative
mortality was 3.5% (95% confidence interval 3.1% to 3.9%), ranging
from 2.7% to 3.8% across the centres. On validation, the incidence of
discrepancies ranged from 0% to 13% for the different risk factors.
The predictive ability of the Parsonnet score measured by area under
the receiver operating characteristic curve was 0.74. The mean
Parsonnet score for the region was 7.0, giving an observed to expected
mortality ratio of 0.51 (range 0.4 to 0.64 across the centres). A new
predictive model was derived from the data by multivariate analysis
which includes nine objective risk factors, all with a significant
association with mortality, which highlights some of the deficits of
the Parsonnet score.
CONCLUSIONS
Risk stratified mortality data were
collected on 100% of patients undergoing adult cardiac surgery in two
years within a defined geographical region and were used to set an
audit standard. Problems with the Parsonnet score of subjectivity,
inclusion of many items not associated with mortality, and the
overprediction of mortality have been highlighted.
Keywords: risk stratification; cardiac surgery; Parsonnet score; audit
© 2000 by Heart
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