Heart 2001;86:262-264 ( September )

Featured clinical case

Late acute thrombosis after paclitaxel eluting stent implantation F Liistro, A Colombo

Cardiac Catheterisation Laboratory, San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy

Correspondence to: Dr Liistro francescoliistro{at}hotmail.com

Accepted 13 June 2001

Late (more than six months) total occlusion after coronary stenting is a progressive phenomenon occurring in approximately 4% of patients, leading to acute myocardial infarction in less than 0.5%. The process must be related to severe and progressive intimal hyperplasia. In patients receiving coronary stenting with simultaneous brachytherapy, late total occlusion has been reported at a higher rate and to be related to stent thrombosis rather than intimal hyperplasia. Late total occlusion presenting with an acute clinical event seven months after the implantation of a paclitaxel drug eluting stent is reported. The occlusion developed soon after the interruption of ticlopidine treatment, suggesting that the event had a thrombotic genesis and that the risk is not confined to the first six month period.


Keywords: paclitaxel eluting stent; late thrombosis

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© 2001 by Heart
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Paclitaxel - Eluting Stents

Anthony H Gershlick

Online, 23 Oct 2001 [Full text]