© 2003 by BMJ Publishing Group & British Cardiac Society
REVIEW
Erectile dysfunction and the cardiovascular patient: endothelial dysfunction is the common denominator
Department of Cardiology, 6th Floor, East Wing, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK
Correspondence to:
Dr G Jackson, Department of Cardiology, 6th Floor, East Wing, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK;
a.cooper{at}cardiocentre.u-net.com
Erectile dysfunction (ED) is a common condition and studies predict that it will become even more common in the future. There is increasing evidence to suggest that it is predominantly a vascular disease and may even be a marker for occult cardiovascular disease. The common pathological process is at the level of the endothelium, and cardiovascular risk factor control may be the key to preventing ED. Many men with established cardiovascular disease have ED. Specific guidelines for the management of ED in these patients have been produced by an expert panel. Cardiovascular risk stratification is an important initial step in managing such patients. In cardiac patients considered to have low cardiovascular risk, the management of ED can be safe and effective.
Keywords: erectile dysfunction; endothelial dysfunction
![]()
CiteULike
Complore
Connotea
Del.icio.us
Digg
Reddit
Technorati What's this?
This article has been cited by other articles:
-
Vardi, Y.
(2009). Microvascular Complications in Diabetic Erectile Dysfunction: Do we need other alternatives?. Diabetes Care
32: S420-S422
[Full Text] -
Aversa, A., Bruzziches, R., Francomano, D., Natali, M., Lenzi, A.
(2009). Testosterone and phosphodiesterase type-5 inhibitors: new strategy for preventing endothelial damage in internal and sexual medicine?. Therapeutic Advances in Urology
1: 179-197
[Abstract] -
Jackson, G.
(2009). Erectile dysfunction in congenital heart disease. Heart
95: 1127-1127
[Full Text] -
Reffelmann, T., Kloner, R. A.
(2009). Phosphodiesterase 5 inhibitors: are they cardioprotective?. Cardiovasc Res
83: 204-212
[Abstract] [Full Text] -
Traish, A. M.
(2009). Androgens Play a Pivotal Role in Maintaining Penile Tissue Architecture and Erection: A Review. J Androl
30: 363-369
[Abstract] [Full Text] -
Jackson, G.
(2009). CHAPTER 15c Erectile Dysfunction. ESC Textbook of Cardiovascular Medicine
2: med-9780199566990-chapter-med-9780199566990-chapter
[Abstract] [Full Text] -
Jamieson, F., Chalmers, J., Duncan, C., Prescott, R. J, Campbell, I. W
(2008). Erectile dysfunction in type 1 diabetic males. British Journal of Diabetes & Vascular Disease
8: 232-234
[Abstract] -
Burnett, A. L.
(2008). Molecular Pharmacotherapeutic Targeting of PDE5 for Preservation of Penile Health. J Androl
29: 3-14
[Abstract] [Full Text] -
Miner, M.
(2007). Engaging Patients in Cardiovascular Disease Risk Reduction: From Empathy to Erectile Dysfunction. AMERICAN JOURNAL OF LIFESTYLE MEDICINE
1: 41-43
[Abstract] -
Jackson, G.
(2006). Erectile dysfunction: a marker of silent coronary artery disease. Eur Heart J
27: 2613-2614
[Full Text] -
Vlachopoulos, C., Aznaouridis, K., Ioakeimidis, N., Rokkas, K., Vasiliadou, C., Alexopoulos, N., Stefanadi, E., Askitis, A., Stefanadis, C.
(2006). Unfavourable endothelial and inflammatory state in erectile dysfunction patients with or without coronary artery disease. Eur Heart J
27: 2640-2648
[Abstract] [Full Text] -
Hellstrom, W. J.G., Egan, R. A., McGee, H. T., Clark, W. M.
(2006). Visual field defect and intracerebral hemorrhage associated with use of vardenafil (Levitra). Neurology
66: 293-294
[Full Text] -
Azadzoi, K. M., Master, T. A., Siroky, M. B.
(2004). Effect of Chronic Ischemia on Constitutive and Inducible Nitric Oxide Synthase Expression in Erectile Tissue. J Androl
25: 382-388
[Abstract] [Full Text] -
Cheitlin, M. D.
(2004). Erectile dysfunction: the earliest sign of generalized vascular disease?. J Am Coll Cardiol
43: 185-186
[Full Text] -
Bivalacqua, T. J., Usta, M. F., Champion, H. C., Kadowitz, P. J., Hellstrom, W. J. G.
(2003). Endothelial Dysfunction in Erectile Dysfunction: Role of the Endothelium in Erectile Physiology and Disease. J Androl
24: S17-S37
[Full Text]
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
