VIEWPOINT

A "natural experiment" in cardiovascular epidemiology in the early 21st century

A Sekikawa¹, B Y Horiuchi², D Edmundowicz¹, H Ueshima³, J D Curb⁴, K Sutton-Tyrrell¹, T Okamura³, T Kadowaki³, A Kashiwagi³, K Mitsunami³, K Murata³, Y Nakamura³, B L Rodriguez⁴, L H Kuller¹

¹ University of Pittsburgh, Pittsburgh, USA
² Hawaii Department of Health, Honolulu, USA
³ Shiga University of Medical Science, Otsu, Japan
⁴ University of Hawaii, Honolulu, USA

Correspondence to:
Correspondence to:
Dr Akira Sekikawa, 3512 Fifth Avenue, Pittsburgh, PA, USA;
akira{at}pitt.edu

Despite similar traditional risk factors, morbidity and mortality rates from coronary heart disease in western and non-western cohorts remain substantially different. Careful study of such cohorts may help identify novel risk factors for CHD, and contribute to the formulation of new preventive strategies

Keywords: epidemiology

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