BRITISH CARDIAC SOCIETY

British Cardiac Society Working Group on the definition of myocardial infarction

K A A Fox¹, J Birkhead², R Wilcox³, C Knight⁴, J Barth⁵

¹ University of Edinburgh, Edinburgh, UK
² Northampton General Hospital, Northampton, UK
³ University Hospital Nottingham, Nottingham, UK
⁴ The London Chest Hospital, London, UK
⁵ Leeds General Infirmary, Leeds, UK

Correspondence to:
Correspondence to:
Professor Keith A A Fox
The Chancellor’s Building, 49 Little France Crescent, University of Edinburgh, Edinburgh EH16 4SB, United Kingdom; k.a.a.fox{at}ed.ac.uk

The British Cardiac Society commissioned this report to help address inconsistencies in the terminology for acute coronary syndromes and wide variations in the threshold for the diagnosis of myocardial infarction (MI) depending on the assay performed, the precision, and the sensitivity. In addition, several publications have highlighted potential problems with the application of the European Society of Cardiology(ESC)/American College of Cardiology (ACC) consensus document published in 2000. A revision process has been initiated under the guidance of the ESC, the ACC, and the American Heart Association (AHA). The purpose of this report is to help inform the next revision of the ESC/ACC/AHA guidelines for the diagnosis of MI.

Keywords: creatine kinase; ST elevation myocardial infarction; myocardial infarction; non-ST myocardial infarction; troponin

Abbreviations: ACC, American College of Cardiology; BCS, British Cardiac Society; CK, creatine kinase; ESC, European Society of Cardiology; FRISC, fast revascularisation during instability in coronary artery disease; GRACE, global registry of acute coronary events; MI, myocardial infarction; PCI, percutaneous coronary intervention; PRAIS-UK, prospective registry of acute ischaemic syndromes in the UK; SPECT, single photon emission computed tomography; TIMI, thrombolysis in myocardial infarction; WHO, World Health Organization

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