© 2004 by BMJ Publishing Group & British Cardiac Society
CASE REPORT
Human coronary morphology after ß radiation brachytherapy of in-stent restenosis
Abteilung fur Kardiologie, Bergmannsleil Bochum, University of Bochum, Germany
Correspondence to:
Correspondence to:
Dr Peter H Grewe
Abteilung fur Kardiologie, Bergmannsleil Bochum, Burkle de la camp Platz 1, Bochum, Germany; petergrewe{at}aol.com
This case report discusses the human coronary morphological findings 18 hours after brachytherapy (ß radiation) of an in-stent restenosis. Brachytherapy produced aseptic inflammation of the periadventitial connective tissue integrating the vasa vasorum in the acute phase. The stent neointima eight months after stenting and acutely 18 hours after radiation consisted of the same cellular components as human stent neointima of specimen not additionally treated with radiation. No evidence of necrosis or excessive fibrotic alterations of the arterial vessel wall have been found.
Keywords: brachytherapy; in-stent restenosis; coronary intervention; stent
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Heart 2004 90: 602.
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