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Heart 2005;91:997-999; doi:10.1136/hrt.2004.053579
Copyright © 2005 BMJ Publishing Group Ltd & British Cardiovascular Society

EDITORIAL

N-acetylcysteine for prevention of radiocontrast induced nephrotoxicity: the importance of dose and route of administration

S J Shalansky1,*, G E Pate2, A Levin3, J G Webb2

1 Pharmacy Department, St Paul’s Hospital, Vancouver, BC, Canada
2 Division of Cardiology, St Paul’s Hospital, Vancouver
3 Division of Nephrology, St Paul’s Hospital, Vancouver

Correspondence to:
Correspondence to:
Stephen Shalansky
PharmD, FCSHP, Pharmacy Department, St Paul’s Hospital, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6; sshalansky{at}providencehealth.bc.ca

ABSTRACT

Dose and route of administration of N-acetylcysteine are key factors to consider when evaluating whether this agent is effective in preventing radiocontrast induced nephropathy

Abbreviations: NAC, N-acetylcysteine; RCIN, radiocontrast induced nephropathy

Keywords: N-acetylcysteine; contrast nephrotoxicity; route of administration


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