EDITORIAL
Clinical trials of endothelin antagonists in heart failure: publication is good for the public health
Clinical Pharmacology Unit, Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK
Correspondence to:
Correspondence to:
D J Webb
Clinical Pharmacology Unit, Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, 3rd Floor East Room E3.22, 47 Little France Crescent, Edinburgh EH16 4TJ, UK; d.j.webb{at}ed.ac.uk
The failure of endothelin antagonists to show benefit in heart failure cannot be understood until all the clinical trials are fully published
Abbreviations: CHF, chronic heart failure; EARTH, Endothelin A Receptor Antagonist Trial in Heart Failure; HEAT, Haemodynamic and Neurohumoral Effects of Selective Endothelin A Receptor Blockade in Chronic Heart Failure; NYHA, New York Heart Association
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