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Published Online First: 11 August 2006. doi:10.1136/hrt.2005.067975
Heart 2007;93:552-558
Copyright © 2007 BMJ Publishing Group Ltd & British Cardiovascular Society

HEART REVIEW

Pregnancy in women with valvular heart disease

Karen K Stout, Catherine M Otto

Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA

Correspondence to:
Dr K K Stout
Division of Cardiology, Box 356422, University of Washington, 1959 Pacific NE, Rm AA522, Seattle, WA 98195, USA; stoutk{at}u.washington.edu

ABSTRACT

Patients with valvular disease who desire pregnancy or are already pregnant require specialised care. Ideally, women undergo preconceptual counselling that addresses any procedures needed to decrease the risks of pregnancy, including valve replacement, if the patient has symptoms at baseline. Management during pregnancy includes replacing any contraindicated medications with safer alternatives, optimising loading conditions, careful monitoring and aggressive treatment of any exacerbating factors. Rarely, percutaneous or surgical intervention is required during pregnancy. Labour and delivery often require invasive haemodynamic monitoring and a multi-disciplinary team for optimal maternal and fetal outcomes.

Abbreviations: UFH, unfractionated


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