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Heart 1997;78:423-425; doi:10.1136/hrt.78.5.423
Copyright © 1997 BMJ Publishing Group Ltd & British Cardiovascular Society

Heart 1997;78:423-425 ( November )

Editorial

Delayed protection against ventricular arrhythmias by cardiac pacing

The first 150 words of the full text of this article appear below.

Although heavy physical exercise, and psychological stress that produces similar physiological responses, may trigger a cardiac event in the immediate (within one hour) postexertion period,1,2 there is prospective evidence that the relative risk of sudden cardiac death and non-fatal myocardial infarction occurring during this period is reduced in individuals who exercise regularly.2,3 The intensity of the exercise required to induce this protection, as well as the time course of this protection, are subjects of ongoing debate3,4; the conclusion that "the protective effect of exercise requires continued exertion"3 implies that the duration of the protection is relatively short lived. The mechanisms of this risk reduction remain unclear but include an increase in baroreflex sensitivity (and increased vagal activity that is antifibrillatory5) and favourable effects on other risk factors.6

Both exercise training7 and right ventricular pacing8,9 confer significant protection against coronary artery occlusion induced ventricular fibrillation in conscious7 and anaesthetised8,9 . . . [Full text of this article]


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  • Wu, Z.-K., Iivainen, T., Pehkonen, E., Laurikka, J., Tarkka, M. R. (2003). Perioperative and postoperative arrhythmia in three-vessel coronary artery disease patients and antiarrhythmic effects of ischemic preconditioning. Eur. J. Cardiothorac. Surg. 23: 578-584 [Abstract] [Full Text]  
  • Brutsaert, D. L. (2003). Cardiac Endothelial-Myocardial Signaling: Its Role in Cardiac Growth, Contractile Performance, and Rhythmicity. Physiol. Rev. 83: 59-115 [Abstract] [Full Text]  
  • Wu, Z.-K., Iivainen, T., Pehkonen, E., Laurikka, J., Tarkka, M. R. (2002). Ischemic Preconditioning Suppresses Ventricular Tachyarrhythmias After Myocardial Revascularization. Circulation 106: 3091-3096 [Abstract] [Full Text]  

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