Heart 1998;80:213-214 ( September )

Editorial

Heart rate variability and cardiac failure

The first 150 words of the full text of this article appear below.

Time and frequency domain analysis of heart rate variability (HRV) has provided adequate information for risk stratification and evaluation of autonomic tone after myocardial infarction.¹ It is therefore not surprising that this non-invasive investigation has been used in patients with cardiac failurethat is, in clinical conditions often characterised by signs of neurohumoral sympathetic activation.

This article reviews some of the most interesting and recent results obtained with the analysis of HRV in patients with cardiac failure, focusing on two principal aspects: the detection of an abnormal autonomic modulation of sinus node, and the prognostic value of reduced HRV.

HRV and neurohumoral activation in cardiac failure

In patients with cardiac failure, when either short term or 24 hour recordings were analysed, reduced HRV was consistently observed and interpreted as a result of predominantly sympathetic and reduced vagal modulation of sinus node.¹ It was also reported that the extent of reduction of . . . [Full text of this article]

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