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Heart 1999;82:5-6; doi:10.1136/hrt.82.1.5
Copyright © 1999 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 1999;82:5-6 ( July )

Editorial

The difficulties in assessing patients with moderate aortic stenosis

The first 150 words of the full text of this article appear below.

Recent insights into the relation between haemodynamic severity and clinical outcome have altered our approach to the patient with moderate valvar aortic stenosis. At the heart of this discussion is the changing definition of "severe" (and hence "moderate") aortic stenosis. Historically, severe stenosis was defined in terms of valve area based on the fluid dynamics concept that flow is not restricted until an orifice is reduced to a quarter its original size. As patients typically underwent cardiac catheterisation only after symptom onset, few data on disease progression or haemodynamic severity in asymptomatic patients were available. However, clinical experience supported this definition and it was used successfully for many years to identify patients likely to benefit from valve replacement.

Relation between haemodynamic severity and clinical symptoms

The first indication that the traditional definition of severe aortic stenosis might need revision came from clinical studies showing substantial overlap in haemodynamic severity between . . . [Full text of this article]


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This article has been cited by other articles:

  • Das, P., Rimington, H., Smeeton, N., Chambers, J. (2003). Determinants of symptoms and exercise capacity in aortic stenosis: a comparison of resting haemodynamics and valve compliance during dobutamine stress. Eur Heart J 24: 1254-1263 [Abstract] [Full Text]  
  • Bermejo, J., Odreman, R., Feijoo, J., Moreno, M. M., Gomez-Moreno, P., Garcia-Fernandez, M. A. (2003). Clinical efficacy of Doppler-echocardiographic indices of aortic valve stenosis:a comparative test-based analysis of outcome. J Am Coll Cardiol 41: 142-151 [Abstract] [Full Text]  
  • McCANN, G P, MUIR, D F, HILLIS, W S (2000). Exercise testing, symptoms, and clinical outcome in aortic stenosis. Heart 83: 103c-103 [Full Text]  

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