Editorial
The difficulties in assessing patients with moderate aortic stenosis
| The first 150 words of the full text of this article appear below. |
Recent insights into the relation between haemodynamic severity and clinical outcome have altered our approach to the patient with moderate valvar aortic stenosis. At the heart of this discussion is the changing definition of "severe" (and hence "moderate") aortic stenosis. Historically, severe stenosis was defined in terms of valve area based on the fluid dynamics concept that flow is not restricted until an orifice is reduced to a quarter its original size. As patients typically underwent cardiac catheterisation only after symptom onset, few data on disease progression or haemodynamic severity in asymptomatic patients were available. However, clinical experience supported this definition and it was used successfully for many years to identify patients likely to benefit from valve replacement.
Relation between haemodynamic severity and clinical symptomsThe first indication that the traditional definition of severe
aortic stenosis might need revision came from clinical studies showing
substantial overlap in haemodynamic severity between
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