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Heart 1999;82:126-127; doi:10.1136/hrt.82.2.126
Copyright © 1999 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 1999;82:126-127 ( August )

Editorial

Matching treatment to the genetic basis of (lipid) disorder in patients with coronary artery disease

The first 150 words of the full text of this article appear below.

Most people of old age in the western society have atherosclerosis to a greater or lesser extent; the condition can almost be regarded as a normal consequence of aging.1 Therefore, the clinical problem of atherosclerosis may be better described by the term "accelerated" atherosclerosis, which reflects the fact that some patients suffer earlier than most from an atherosclerotic process. It is this acceleration of atherosclerotic disease progression that is usually the subject of investigation.

Establishing the rate of progression of coronary atherosclerosis in patients is important as progression of the disease is one of the major factors that determines clinical prognosis.2 3 Therefore, identifying patients at risk for increased progression of coronary artery disease (CAD) is important as these patients might benefit from early (lipid lowering) treatment. Thus far, it has proved difficult to identify patients at increased risk when lipoprotein disturbances are moderate, which is the case for most patients . . . [Full text of this article]


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This article has been cited by other articles:

  • WILKINS, M. R, ROSES, A. D, CLIFFORD, C P. (2000). Pharmacogenetics and the treatment of cardiovascular disease. Heart 84: 353-354 [Full Text]  

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