Heart 2000;83:81-85 ( January )

Review

Clinical significance of the bicuspid aortic valve

C Ward

North West Regional Cardiac Centre, South Manchester University NHS Trust, Southmoor Road, Manchester M23 9LT, UK

Accepted 4 August 1999

The first 150 words of the full text of this article appear below.

	Introduction

The association of bicuspid aortic valve with aortic stenosis, aortic regurgitation, and infective endocarditis has been known for almost 150 years and with dissection of the aorta for 75 years.¹ These complications are mentioned only briefly in cardiology textbooks³ and a standard work on medical insurance underwriting⁴ implies that it is usually a benign lesion: when diagnosed at routine medical examination and if the valve is functionally normal, insurance is offered at ordinary rates. The authors also state "If there is no stenosis by age 20 years (defined as a peak gradient of less than 40 mm Hg) and only trivial insufficiency, there is an excellent chance that significant haemodynamic change will not develop before age 70." However, on the basis of published reports by this age the majority of patients will have died or developed serious symptoms requiring surgical intervention. This review summarises the major studies that provide information on the incidence, pathology, . . . [Full text of this article]

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