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Heart 2000;83:621-626; doi:10.1136/heart.83.6.621
Copyright © 2000 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 2000;83:621-626 ( June )

Review

Management of cardiogenic shock complicating acute myocardial infarction: towards evidence based medical practice

S G Williams, D J Wright, L B Tan

Cardiology Research, Yorkshire Heart Centre, Leeds General Infirmary, Leeds LS1 3EX, UK

Correspondence to: Dr Tan

Accepted 8 March 2000

The first 150 words of the full text of this article appear below.

    Introduction

The treatment of cardiogenic shock is the ultimate challenge of our ability to manage patients presenting with acute myocardial infarction. Despite advances in the treatment of infarcts with thrombolysis, there has been no significant decrease in the incidence of cardiogenic shock, which has remained at 7-10% during the last 20 years.1-5 Hospital mortality was over 90% in the 1970s6 and is still high, in the region of 45-80%, in the 1990s.1 7-9 Attitudes towards treatment of cardiogenic shock range from resignation, providing supportive measures only, to aggressive intervention. In the era of evidence based medical practice, are there data to support adoption of either extreme of approach?


    Registry of cardiogenic shock patients

The largest prospectively identified registry of patients with cardiogenic shock so far analysed is from the GUSTO-I (global utilisation of streptokinase and tissue plasminogen activator for occluded coronary arteries) trial.4 8 10 Of the 41 021 patients recruited into that study, 7.2% (2972) developed cardiogenic shock, with an . . . [Full text of this article]


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This article has been cited by other articles:

  • Garcia-Gonzalez, M. J., Dominguez-Rodriguez, A., Ferrer-Hita, J. J., Abreu-Gonzalez, P., Munoz, M. B. (2006). Cardiogenic shock after primary percutaneous coronary intervention: Effects of levosimendan compared with dobutamine on haemodynamics. Eur J Heart Fail 8: 723-728 [Abstract] [Full Text]  
  • Lindholm, M.G., Aldershvile, J., Sundgreen, C., Jorgensen, E., Saunamaki, K., Boesgaard, S. (2003). Effect of early revascularisation in cardiogenic shock complicating acute myocardial infarction. A single center experience. Eur J Heart Fail 5: 73-79 [Abstract] [Full Text]  
  • Marber, M.S., Redwood, S.R. (2001). The management of cardiogenic shock: can anything be learnt from registries?. Eur Heart J 22: 444-445  

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