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Heart 2001;85:249-250; doi:10.1136/heart.85.3.249
Copyright © 2001 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 2001;85:249-250 ( March )

Editorial

Do patients over 40 years of age benefit from closure of an atrial septal defect?

The first 150 words of the full text of this article appear below.

There are few topics in adult congenital heart disease as persistently debated as the management of atrial septal defects (ASDs). The paper by Jemielity and colleagues in this issue of Heart reactivates these fires.1 Their retrospective study includes 88 largely symptomatic patients who received surgical closure of secundum and sinus venosus ASDs. Their age range at surgery was 40-62 years, with a mean of 46 years. They were followed for 1-17 years, mean 6.9 years. There was only one operative death. Functional class improved strikingly from 62% in New York Heart Association (NYHA) functional class III and IV preoperatively to 82% in NYHA class I and II postoperatively. Pulmonary vascularity improved on x ray, and right ventricular size diminished as assessed by echocardiography. Atrial flutter and fibrillation continued to be troublesome. This study adds additional evidence to the proposition that closure of secundum and sinus venosus ASDs benefits many or most symptomatic patients . . . [Full text of this article]


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This article has been cited by other articles:

  • Schoen, S.P., Zimmermann, T., Kittner, T., Braun, M.U., Fuhrmann, J., Schmeisser, A., Strasser, R.H. (2007). NT-proBNP correlates with right heart haemodynamic parameters and volumes in patients with atrial septal defects. Eur J Heart Fail 9: 660-666 [Abstract] [Full Text]  
  • Swan, L, Gatzoulis, M.A (2003). Closure of atrial septal defects: is the debate over?. Eur Heart J 24: 130-132 [Full Text]  
  • Auer, J., Punzengruber, C., Berent, R., Porodko, M., Eber, B. (2001). Elevated Cardiac Troponin I Following Heavy-Resistance Exercise in Ostium Secundum Type-Atrial Septal Defect. Chest 120: 1752-1753 [Full Text]  

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