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JOURNALSCAN |
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ISCHAEMIC HEART DISEASE |
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Older people seem at major risk of cognitive dysfunction after CABG: There is a risk of stroke after coronary bypass grafting (CABG), but also a risk of cognitive dysfunction. Newman and colleagues undertook detailed evaluation up to five years and found that over 50% of patients have a decline in cognitive function at discharge, and 24% have a decline at six months. Worryingly, the number rises again to 42% at five years compared to preoperatively. The effect was most dramatic in the over 70s. Part of the observed effect is an age related decline, and part was associated with any operation, but the concern remains that cardiopulmonary bypass and aortic manipulation have long term effects on the brain.
1 Newman M, Kirchner J, Phillips-Bute
B, Gaver V, Grocott H, Jones RH, Mark DB, Reves JG, Blumenthal JA.
Longitudinal
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