Review
Echocardiographic differentiation of pathological and physiological left ventricular hypertrophy
D J R Hildick-Smith, L M ShapiroCardiac Unit,
Papworth Hospital, Cambridge CB3 8RE, UK
Correspondence to: Dr Hildick-Smith david.hildick-smith@papworth-tr.anglox.nhs.uk
Accepted 13 February
2001
| The first 150 words of the full text of this article appear below. |
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Introduction |
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Left ventricular hypertrophy is a serious condition, strongly associated with the development of coronary artery disease, cerebrovascular disease, cardiac failure, sudden cardiac death, and overall mortality.1-4 In addition, regression of left ventricular hypertrophy is associated with reduction in all cause and cardiovascular mortality. The existence, therefore, of left ventricular hypertrophy in apparently healthy people has generated considerable interest ever since its initial description.5 Debate has centred on two major issues. The first concerns the nature of left ventricular hypertrophy of athleticism: is it simply a physiological response to periodic myocardial loading or does it have a pathological component and therefore carry implications for long term prognosis? The second concerns the diagnosis of left ventricular hypertrophy of athleticism: is it possible to differentiate with confidence physiological left ventricular hypertrophy from pathological conditions?
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Physiology and pathology a continuum or separate entities? |
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Cardiac enlargement in response to long term training was first
described a century ago and was considered to be
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a continuum or separate entities?