Education in Heart
CONGENITAL HEART DISEASE
Heart disease and pregnancy
Samuel C Siu, Jack M ColmanUniversity of Toronto Congenital Cardiac Centre for Adults,
University Health Network and Mount Sinai Hospital, Toronto,
Ontario,
Canada
Correspondence to: Samuel Siu MD, PMCC 3-526, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada Sam.Siu@uhn.on.ca
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Introduction |
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Pregnancy in most women with heart disease has a favourable maternal and fetal outcome. With the exception of patients with Eisenmenger syndrome, pulmonary vascular obstructive disease, and Marfan syndrome with aortopathy, maternal death during pregnancy in women with heart disease is rare.1-4 However, pregnant women with heart disease do remain at risk for other complications including heart failure, arrhythmia, and stroke. Women with congenital heart disease now comprise the majority of pregnant women with heart disease seen at referral centres. The next largest group includes women with rheumatic heart disease. Peripartum cardiomyopathy, though infrequent, will be discussed in view of its unique relation to pregnancy. Two groups of conditions not discussed further are coronary artery disease, infrequently encountered, and isolated mitral valve prolapse, which generally has an excellent outcome.
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Cardiovascular physiology and pregnancy |
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Hormonally mediated increases in blood volume, red cell mass, and
heart rate result in a major increase in cardiac output during
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