Editorial
Coronary angiography cannot be used to assess myocardial perfusion in patients undergoing reperfusion for acute myocardial infarction
| The first 150 words of the full text of this article appear below. |
"All
knowledge, like all ignorance, deviates from the truth in an
opportunistic direction"
Gunnar Myrdal from A
challenge to world poverty
Perfusion can be defined as tissue blood flow at the capillary level.
There are two components of flowvolume and velocity. Blood flow is a
volume of blood moving at a certain velocity. Approximately 8% of the
left ventricular mass at rest is blood (the blood volume fraction of
the myocardium1), about 90% of which is resident in
capillaries.2 The red blood cell velocity in the
myocardium is approximately 1 mm/s at rest.3 Myocardial blood flow at rest is approximately 1 ml/min/g.
Because there are no arteriovenous connections in the human heart, any
blood entering the coronary artery will reach the capillaries under
normal circumstances. Consequently, flow measured at any levelcoronary arteries, arterioles, or capillarieswill reflect tissue perfusion. If flow is reduced in a coronary artery in the
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