Journal scan
| The first 150 words of the full text of this article appear below. |
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JOURNALSCAN |
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Please
visit the Heart website (www.heartjnl.com) for links to these
articles
many to full text.
IQBAL MALIK
Editor, JournalScan
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ISCHAEMIC HEART DISEASE |
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Clopidogrel for all
acute coronary syndromes? JournalScan mentioned the CURE trial
when it was presented at the American College of Cardiology meeting
earlier this year (Heart 2001;86:15[Full Text]). The full paper is now
published. Clopidogrel in addition to aspirin reduces the risk of
death/myocardial infarction (MI) and stroke by 20% if given to all
patients with non-ST elevation acute coronary syndromes. At present,
clopidogrel is only used after stent implantation in the UK. The CURE
study showed similar benefits in low, medium, and higher risk patients
(such as those with ST depression, positive troponins, or haemodynamic
instability). Initiating treatment in all patients with acute coronary
syndromes awaiting transfer for in-patient angiography is probably
merited. The CURE investigators suggest that this group has a 28%
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