© 2002 by Heart
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Ischaemic heart disease
High incidence of undiagnosed diabetes mellitus in patients with AMI 
Of 181 consecutive non-diabetic patients with acute myocardial infarction (AMI), 35% (95% confidence interval (CI) 28% to 43%) and 40% (95% CI 32% to 48%) had impaired glucose tolerance at discharge and after three months, respectively, while 31% (95% CI 24% to 38%) and 25% (95% CI 18% to 32%) had previously undiagnosed diabetes mellitus. Independent predictors of abnormal glucose tolerance at three months were concentrations of HbA1c at admission (p = 0.024) and fasting blood glucose concentrations on day 4 (p = 0.044).
Norhammar A, Tenerz Å, Nilsson G, Hamsten A, Efendíc S, Rydén L, Malmberg K. Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study. Lancet 2002;359:2140–4.[Medline]
Prevention of NIDDM with acarbose Over 1400 patients with impaired glucose tolerance were randomly allocated to 100 mg
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