EDITORIAL

The CARDia trial protocol

D Smith

Correspondence to:
Correspondence to:
Dr David Smith, Department of Cardiology, Royal Devon and Exeter Hospital, Exeter, Devon, UK;
dagobert@eurobell.co.uk

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The question of which revascularisation strategy is best in diabetics is a very important one, and it demands a robust answer

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Keywords: angioplasty; stent; diabetes; restenosis

Abbreviations: ARTS, arterial revascularisation therapy study; BARI, bypass angioplasty revascularisation investigation; CABG, coronary artery bypass grafting; CARDia, coronary artery revascularisation in diabetes; EAST, Emory angioplasty versus surgery trial; PCI, percutaneous coronary intervention; RITA, randomised intervention treatment of angina; SoS, stent or surgery

The first 150 words of the full text of this article appear below.

An earlier edition of the web based version of Heart (May 2003) saw the electronic publication of the protocol of the CARDia (coronary artery revascularisation in diabetes) trial. The CARDia trial is a multi-centre, "prospective, randomised comparison of optimal coronary angioplasty—with use of stenting and abciximab recommended—versus up to date coronary artery bypass grafting in patients with diabetes mellitus suitable for either intervention". It will recruit 600 patients through 20 centres over a two year period. Patients suitable for either procedure will be randomised to percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). The PCI group will be further randomised to receive bare stents or rapamycin eluting stents.

The publication of a trial protocol is a new departure for Heart but follows precedents in other journals when important trials are planned or underway. It might at first sight seem odd to publish protocols of trials in peer review . . . [Full text of this article]

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