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Heart 2003;89:1281-1282; doi:10.1136/heart.89.11.1281
Copyright © 2003 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 2003;89:1281-1282
© 2003 by BMJ Publishing Group & British Cardiac Society

EDITORIAL

Diastolic heart failure: fact or fiction?

J E Sanderson

Correspondence to:
Correspondence to:
Professor John E Sanderson, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong;
jesanderson@cuhk.edu.hk


It is logical to find some abnormalities of systolic function in those with "diastolic" heart failure, just as it is well established that diastolic dysfunction is an integral part of systolic heart failure

Keywords: diastole; left ventricular function; heart failure; systole

The first 150 words of the full text of this article appear below.

The concept of "diastolic" heart failure grew out of the observation that many patients who had the symptoms and signs of heart failure had an apparently normal left ventricular (LV) ejection fraction (> 0.45). Thus it was assumed that since systolic function was "preserved" the problem must lie in diastole, although it is not clear by whom or when this assumption was made. Nevertheless, many guidelines followed on how to diagnose "diastolic" heart failure backed up by indicators of diastolic dysfunction derived from Doppler echocardiography,1–3 and it was found to be common.4 This edifice is, however, built on a number of assumptions that are looking increasingly shaky. For example, is the ejection fraction a good index of LV systolic function? Can diastolic function or dysfunction be measured accurately? And in any case can systole be separated so neatly from diastole?

EJECTION FRACTION

The ejection fraction has proved to be a robust measurement . . . [Full text of this article]


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  • De Keulenaer, G. W., Brutsaert, D. L. (2007). Systolic and diastolic heart failure: Different phenotypes of the same disease?. Eur J Heart Fail 9: 136-143 [Abstract] [Full Text]  
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  • Lim, T. K., Ashrafian, H., Dwivedi, G., Collinson, P. O., Senior, R. (2006). Increased left atrial volume index is an independent predictor of raised serum natriuretic peptide in patients with suspected heart failure but normal left ventricular ejection fraction: Implication for diagnosis of diastolic heart failure. Eur J Heart Fail 8: 38-45 [Abstract] [Full Text]  
  • Sanderson, J. E. (2005). Diastolic Dysfunction and Doppler Echocardiography. J Am Coll Cardiol 45: 2095-2095 [Full Text]  

eLetters:

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Heart failure with preserved systolic function: is the legitimacy of the term of 'diastolic heart fa
Stephane Arques
Online, 21 Nov 2003 [Full text]

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