© 2003 by BMJ Publishing Group & British Cardiac Society
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Ischaemic heart disease
The evidence for the benefits of primary angioplasty over thrombolysis is strengthened further by the latest meta-analysis. Primary angioplasty was better than thrombolytic treatment at reducing overall short term death (7% v 9%; p = 0.0002), non-fatal reinfarction (3% v 7%; p < 0.0001), stroke (1% v 2%; p = 0.0004), and the combined end point of death, non-fatal reinfarction, and stroke (8% v 14%; p < 0.0001). The results seen with primary angioplasty remained better than those seen with thrombolytic treatment during long term follow up, and were independent of both the type of thrombolytic agent used, and whether or not the patient was transferred for primary angioplasty.
Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet 2003;361:13–20.[CrossRef][Medline]
After a host of trials suggesting statins lower coronary heart disease (CHD)
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