© 2003 by BMJ Publishing Group & British Cardiac Society
EDITORIAL
Stress and myocardial infarction
The Heart Institute, Good Samaritan Hospital, Division of Cardiovascular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Correspondence to:
Correspondence to:
Professor Robert A Kloner, The Heart Institute, Good Samaritan Hospital, 1225 Wilshire Blvd, Los Angeles, CA 90017, USA;
rkloner@goodsam.org
Could there be a relation between cardiovascular events and environmental stress in the form of sporting events, making winning or losing a life or death issue?
Keywords: stress; myocardial infarction
| The first 150 words of the full text of this article appear below. |
Myocardial infarction (MI) is a serious health problem which causes substantial morbidity and mortality. The seriousness of coronary artery disease is heightened by the fact that approximately a third of patients present with sudden death as their first manifestation,1 and efforts to prevent infarctions before they occur have fuelled an area of research which investigates inciting events, or "triggers", of MI, arrhythmias, and sudden death. The idea that an MI can be incited by an identifiable event is an old one, but research into cardiovascular triggers has only recently begun to elucidate specific culprits. Triggering research continues to evolve in concert with our understanding of the pathophysiological mechanisms involved in MI, with the eventual hope of developing effective preventive strategies.
The circadian rhythm in the incidence of cardiac events was one of the first triggering patterns to be discovered; peak frequencies of MI and sudden cardiac death were observed in
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