© 2004 by BMJ Publishing Group & British Cardiac Society
JournalScan
| The first 150 words of the full text of this article appear below. |
ISCHAEMIC HEART DISEASE
Patients with acute coronary syndrome (ACS) need lipid lowering agents. How low should the LDL (low density lipoprotein) cholesterol value go? A total of 4162 patients who had ACS < 10 days before received either 40 mg of pravastatin (standard treatment) or 80 mg of atorvastatin daily (intensive treatment). The primary end point was a composite of death from any cause, myocardial infarction, documented unstable angina requiring rehospitalisation, revascularisation (performed at least 30 days after randomisation), and stroke. Follow up lasted a mean of two years. The median LDL cholesterol concentration achieved during treatment was 95 mg/dl (2.46 mmol/l) in the standard dose pravastatin group and 62 mg/dl (1.60 mmol/l) in the high dose atorvastatin group (p < 0.001). Kaplan-Meier estimates of the rates of the primary end point at two years were 26.3% in the pravastatin group versus 22.4% in the atorvastatin group (16% reduction in favour of atorvastatin,
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
