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Heart 2004;90:999-1002; doi:10.1136/hrt.2003.028852
Copyright © 2004 BMJ Publishing Group Ltd & British Cardiovascular Society
Heart 2004;90:999-1002
© 2004 by BMJ Publishing Group & British Cardiac Society

MINI-SYMPOSIUM

Revascularisation in diabetics with multivessel coronary artery disease

K J Beatt, K P Morgan, A Kapur

Hammersmith Hospitals NHS Trust, London, UK

Correspondence to:
Correspondence to:
Dr Kevin J Beatt
Hammersmith Hospitals NHS Trust, Du Cane Road London, UK; k.beatt@imperial.ac.uk

Abbreviations: BARI, bypass angioplasty revascularisation investigation; CABG, coronary artery bypass graft surgery; CABRI, coronary angioplasty versus bypass revascularisation; CREDO, clopidogrel for the reduction of events during observation; CVA, cerebrovascular accident; DES, drug eluting stents; DM, diabetes mellitus; EAST, Emory angioplasty versus surgery trial; EPIC, evaluation of 7E3 for the prevention of ischaemic complications; EPILOG, evaluation in PTCA to improve long-term outcome with abciximab GP IIb/IIIa blockade; EPISTENT, evaluation of platelet IIb/IIIa inhibition for stenting; GABI, German angioplasty bypass surgery investigation; LAD, left anterior descending coronary artery; LIMA, left internal mammary artery; MASS, medicine angioplasty or surgery study; MACE, major adverse cardiac events, MI, myocardial infarction; PCI, percutaneous coronary angioplasty; RITA, randomised intervention of angina; TLR, target lesion revascularisation; TVR, target vessel revascularisation

Keywords: diabetics; revascularisation; multivessel coronary artery disease; stents

The first 150 words of the full text of this article appear below.

Diabetic patients are recognised as being at high risk of vascular complications in a variety of situations. Approximately 80% will die of a cardiovascular event. In recent years there has been increasing recognition of the diversity of mechanisms responsible for prevalence of adverse events, although there are still many aspects that are poorly understood. Coronary artery disease is the major cause of death among diabetics and tends to be more severe and diffuse in this group. The growth of the diabetic population combined with recent technological and pharmacological advances in both bypass surgery and angioplasty make choosing the optimum revascularisation strategy in this group one of the most challenging issues facing the cardiologist today.

The exponential relation between the risk of developing diabetes mellitus (DM) and increasing body mass index ensures that the incidence of type 2 DM will rapidly increase if the current trend in western countries of increasing . . . [Full text of this article]


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