© 2004 by BMJ Publishing Group & British Cardiac Society
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E. Liodakis, O. Al Shareef, D. Dawson, P. Pearson, P. Nihoyannopoulos.Hammersmith Hospital, London, UK
Introduction: Electrical asynchrony is often observed in patients suffering from left ventricular dysfunction. Previous studies have shown that when electrical asynchrony is used as a selection criterion for cardiac resynchronization therapy (CRT), 30% of the patients do not respond to this treatment. Mechanical asynchrony expressed with the Dysynchrony Index (DI), which derives by calculating the standard deviation of the time for each of the 16 segments of the Left Ventricle, as defined by the American Society of Echocardiography (ASE), to reach its minimum volume, is also a major finding in patients suffering from heart failure. In this study we assessed the ability of real time 3D echocardiography (RT3DE) to quantify mechanical asynchrony, as well as the correlation between the DI and the QRS length.
Methods: We investigated 40 patients with any degree of left ventricular
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