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Heart 2005;91:1631-1632
Copyright © 2005 BMJ Publishing Group Ltd & British Cardiovascular Society

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Iqbal Malik, Editor

The first 150 words of the full text of this article appear below.


ISCHAEMIC HEART DISEASE

Another new risk marker in coronary heart disease {blacktriangleright}

After a spate of new inflammatory markers that appear to predict risk, this study of a very high risk population of patients (8% death rate at 12 months) having coronary angiography, suggests that having low levels of endothelial progenitor cells in your blood elevates cardiovascular risk. After adjustment for age, sex, vascular risk factors, and other relevant variables, increased levels of endothelial progenitor cells were associated with a reduced risk of death from cardiovascular causes (hazard ratio (HR) 0.31, 95% confidence interval (CI) 0.16 to 0.63; p = 0.001), a first major cardiovascular event (HR 0.74, 95% CI 0.62 to 0.89; p = 0.002), revascularisation (HR 0.77; 95% CI 0.62 to 0.95; p = 0.02), and hospitalisation (HR 0.76, 95% CI 0.63 to 0.94; p = 0.01). Endothelial progenitor cell levels were not predictive of MI or of death from all causes. This marker is not yet ready for "prime . . . [Full text of this article]


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