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Definition of acute coronary syndrome

I N Findlay¹, A D Cunningham²

¹ Royal Alexandra Hospital, Paisley, UK
² National Clinical Audit Support Programme, NHS Information Authority, Tavistock House, London, UK

Correspondence to:
Correspondence to:
Dr Iain N Findlay
Royal Alexandra Hospital, Corsebar Road, Paisley, PA2 9PN, UK; Iain.Findlay@rah.scot.nhs.uk

Abbreviations: ACS, acute coronary syndrome; BCS, British Cardiac Society; CK, creatine kinase; MINAP, Myocardial Infarction National Audit Project; TnI, troponin I; TnT, troponin T

Keywords: acute coronary syndrome; creatine kinase; troponin I; troponin T

The first 150 words of the full text of this article appear below.

The British Cardiac Society (BCS) Working Group on the definition of acute myocardial infarction¹ presents a pragmatic and practical nomenclature for acute coronary syndromes (ACS) and sets definite cut off points for troponin T (TnT) and troponin I (TnI).

We reviewed retrospectively the relation between TnT and creatine kinase (CK) in 978 admissions to our cardiac care unit (over a three year period) who survived to discharge. Criteria for inclusion were simple—that the final discharge diagnosis be recorded, and that patients survive to discharge and had TnT and a peak CK recorded. No attempt was made to correct for sampling time. Our aim was to establish a cut off value for TnT to be equivalent to twice our upper limit of normal for CK (2 x 190 = 380 IU). The mean TnT was 1.09 ng/ml and the mean CK was 433 IU. The correlation between the two, while significant, . . . [Full text of this article]

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