© 2005 by BMJ Publishing Group & British Cardiac Society
MINI-SYMPOSIUM
Fetal origins of adult disease: introduction
Correspondence to:
Correspondence to:
Professor Mark Hanson
Centre for Developmental Origins of Health and Disease, University of Southampton, Princess Anne Hospital, Southampton, UK; m.hanson@soton.ac.uk
Keywords: fetal origins; heart disease
| The first 150 words of the full text of this article appear below. |
It is becoming clear that, while the number of people dying from heart disease continues to fall each year in countries such as the UK, the number of people suffering from this disease is rising.1 In part this is due to the age structure of developed societies, but it also emphasises that we are still far from understanding the causes of heart disease. Until we do, prevention will be difficult. The concept that prenatal and early childhood factors play an important role in this aetiology is now well established2 and this theory and its implications are being explored.3,4
The collection of short reviews in this symposium highlights areas of current research of direct relevance to cardiovascular disease. Mark Hanson and Peter Gluckman examine how their concept of predictive adaptive responses may be applied to vascular endothelial dysfunction, as this plays a key role in the development of vascular and related
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