© 2005 by BMJ Publishing Group & British Cardiac Society
MINI-SYMPOSIUM
Fetal roots of cardiac disease
Heart Research Center, Oregon Health & Science University, Portland, Oregon, USA
Correspondence to:
Correspondence to:
Professor Kent L Thornburg
Heart Research Center, L464, Oregon Health & Science University, 3181 Sam Jackson Park Road, Portland, Oregon 97239, USA; thornbur@ohsu.edu
Keywords: cardiomyocytes; fetal roots; cardiac disease
| The first 150 words of the full text of this article appear below. |
In western countries, cardiovascular disease is the leading killer of men and women. In the past decade, it has become increasingly clear that women are just as vulnerable to heart disease as men. In 2004, the number of women with some form of the disease will exceed the number of such men in the USA (www.americanheart.org). While new medical treatments are prolonging the lives of people with cardiovascular disease, an increasing number of men and women are living with cardiovascular limitations or outright heart failure. The total estimated cost of cardiovascular disease in the USA will exceed $300 billion in 2004. In the coming decades, the disease burden that is directly attributable to cardiovascular disease is expected to increase dramatically in developing countries.
The American Heart Association (AHA) has identified risk factors that were derived from statistical associations with the incidence of coronary disease (www.americanheart.org). Some
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