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Heart 2006;92:124-130; doi:10.1136/hrt.2005.063719
Copyright © 2006 BMJ Publishing Group Ltd & British Cardiovascular Society

EDUCATION IN HEART

Valve disease

Management of infective endocarditis

Gilbert Habib

Correspondence to:
Correspondence to:
Dr Gilbert Habib
Hôpital Timone, Cardiologie B, Boulevard Jean Moulin, 13005 Marseille, France; gilbert.habib@ap-hm.fr

Keywords: infectious endocarditis

The first 150 words of the full text of this article appear below.

Infective endocarditis (IE) is a disease that is continually changing, with new high risk patients, new diagnostic procedures, the involvement of new microorganisms, and new therapeutic methods.1 Despite knowledge of these changes, and considerable improvements in diagnostic and therapeutic strategies, IE is still a severe disease.2 The high morbidity and mortality rate of IE is the consequence of both the destructive valvar lesions causing valve regurgitation and heart failure, and the valvar vegetations with their high embolic potential. Although the incidence of IE is relatively stable, those patients affected by the disease are older and sicker, and the co-morbidity rate is high.3 As soon as the diagnosis of IE is suspected, the physician is faced with four specific problems:

  • First, the diagnosis of IE is still difficult and is frequently delayed, causing progressive and irreparable valvar damage.
  • Second, IE is still associated with high in-hospital mortality, ranging from . . . [Full text of this article]


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