EDUCATION IN HEART
Coronary disease
Management of dyslipidaemias
1 Division of Cardiology, University of Washington/Harborview Medical Center, Seattle, Washngton, USA
2 Division of Endocrinology, Metabolism & Nutrition, University of Washington/Harborview Medical Center
Correspondence to:
Correspondence to:
Pathmaja Paramsothy
MD, Department of Internal Medicine, Division of Cardiology, Harborview Medical Center, 325 9th Avenue, Box 359748, Seattle, WA 98104, USA; nmbob@u.washington.edu
Keywords: prevention; lipid disorder; dyslipidaemia; cardiovascular disease
| The first 150 words of the full text of this article appear below. |
Atherosclerotic disease is the leading cause of death among men and women in Europe, the United States, and worldwide.1,2 Previously considered a "western" disease, it is now clear that various peoples of diverse ethnic backgrounds are vulnerable to atherosclerosis. The epidemic of obesity, especially abdominal obesity, escalates the need for appropriate detection and management of high risk individuals. The overwhelming consumption of economic and medical resources necessitates preventive measures in order to decrease the global burden of heart disease. The recent Interheart study, a very large case–control study of acute myocardial infarction in 52 countries, demonstrates that traditional risk factors for coronary heart disease (CHD) account for most of the risk worldwide (over 90%) and include abnormal lipids, smoking, diabetes, hypertension, abdominal obesity, psychosocial factors, diminished consumption of fruits and vegetables, lack of regular alcohol intake, and lack of regular physical activity. The two most potent risk factors
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