EDUCATION IN HEART

General cardiology

Role of B-type natriuretic peptide (BNP) and NT-proBNP in clinical routine

Michael Weber, Christian Hamm

Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany

Correspondence to:
Correspondence to:
Michael Weber
MD, Kerckhoff Heart Center, Department of Cardiology, Benekestraße 2–8, 61231 Bad Nauheim, Germany; M.Weber@kerckhoff-klinik.de

Keywords: B-type natriuretic peptide; BNP; NT-proBNP; heart failure; coronary artery disease

The first 150 words of the full text of this article appear below.

In recent years biomarkers have emerged as important tools for diagnosis, risk stratification and therapeutic decision making in cardiovascular diseases. Cardiac troponins in particular have become the cornerstone for diagnostic work up of patients with acute coronary syndromes. Currently, several promising new biomarkers are under scientific investigation. Most of these new biomarkers, however, are not yet suitable for clinical application, with the exception of B-type natriuretic peptide (BNP) and its N-terminal fragment (NT-proBNP). Both markers have proven their diagnostic usefulness in a great number of studies and thus have progressed from bench to clinical application. This article aims to summarise existing data concerning BNP and NT-proBNP measurement in cardiovascular disorders and to outline how these markers can be integrated into clinical routine. Furthermore, future perspectives of these markers will be discussed.

PHYSIOLOGY

B-type natriuretic peptide, which is also called brain-type natriuretic peptide (BNP), was first described in 1988 after . . . [Full text of this article]

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