EDUCATION IN HEART
Valve disease
Aortic regurgitation
Correspondence to:
Correspondence to:
Professor Gerald Maurer
Division of Cardiology, Medical University of Vienna, AKH, Waehringer Guertel 18-20, 1090 Vienna, Austria; gerald.maurer@meduniwien.ac.at
| The first 150 words of the full text of this article appear below. |
The incidence of clinically significant aortic regurgitation (AR) increases with age, typically peaking in the fourth to sixth decade of life. It is more common in men than women. The prevalence of AR in the Framingham study was reported to be 4.9%, with regurgitation of moderate or greater severity occurring in 0.5%.
AETIOLOGY OF AORTIC REGURGITATION
AR may be caused by malfunction of the valve leaflets themselves, by dilatation of the aortic root and annulus, or may be due to a combination of these factors (table 1
). Rheumatic disease is still the most common aetiology of AR in developing countries; however, in Western Europe and North America the leading cause of AR is either congenital (particularly due to bicuspid leaflets) or degenerative disease, including annuloaortic ectasia. Understanding the mechanism leading to AR is essential for proper patient management, including the surgical approach. Thus, knowledge of the morphology of the valve leaflets,
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