EDUCATION IN HEART
Congenital heart disease
Tetralogy of Fallot: from fetus to adult
1 Department Paediatric Cardiology, Royal Brompton Hospital, London, UK
2 Adult Congenital Heart Unit, Royal Brompton Hospital, London, UK
3 Brompton Fetal Cardiology, Royal Brompton Hospital, London, UK
Correspondence to:
Correspondence to:
Dr Elliot A Shinebourne
Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK; e.shinebourne@rbht.nhs.uk
Keywords: tetralogy of Fallot; fetal echocardiography; follow up; sudden death; restrictive right ventricle
| The first 150 words of the full text of this article appear below. |
Tetralogy of Fallot (ToF) occurs in approximately 1 in 3600 live births and accounts for 3.5% of infants born with congenital heart disease. Surgical repair was first introduced in the 1950s and there is now a large population of adults with repaired tetralogy. Many of the short term aspects of management have been resolved, although whether symptomatic neonates should undergo primary repair or first be palliated remains debatable. In 2001, independently validated data pooled from all 13 centres performing cardiac surgery in the United Kingdom indicated a 97% survival one year after operation.1 Other reports indicate that of patients alive 30 days after operation there is a 98% 20 year survival, and of those operated on as children 30 year survival is above 90%.2
This has focused attention on long-term follow up as many patients with repaired ToF are now middle-aged. Given that this population includes patients
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