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GENERAL CARDIOLOGY
The extent of myocardial injury during coronary artery bypass surgery (CABG) is associated with subsequent patient morbidity and mortality. One potential way to limit this damage is by the use of remote ischaemic preconditioning, whereby several brief episodes of ischaemia in one region or organ protects other tissues or organs, such as the heart, from a subsequent sustained episode of ischaemia. Studies to date have shown that brief ischaemia of non-cardiac tissues such as the kidney, intestine or skeletal muscle may also protect the myocardium. Hausenloy et al aimed at assessing whether transient episodes of ischaemia in one arm could reduce myocardial injury in adults with coronary artery disease undergoing elective CABG.
Fifty-seven adult patients undergoing elective CABG were randomly assigned to receive intervention, defined as three 5-minute cycles of right upper arm ischaemia by inflating a blood pressure cuff up to 200 mm Hg, or control treatment, where a
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