Heart 2007;93:372-374
SCIENTIFIC LETTER
Outcomes after implantable cardioverter-defibrillator treatment in children with hypertrophic cardiomyopathy
1 Inherited Cardiovascular Diseases Unit, Great Ormond Street Hospital, London, UK
2 St Bartholomew’s Hospital, London, UK
Correspondence to:
Dr P M Elliott
The Heart Hospital, 16-18 Westmoreland Street, London W1G 8PH, UK; perry.elliott@uclh.nhs.uk
Accepted 9 August 2006
Abbreviations: HCM, hypertrophic cardiomyopathy; ICD, implantable cardioverter-defibrillator; SCD, sudden cardiac death
| The first 150 words of the full text of this article appear below. |
Implantable cardioverter-defibrillators (ICDs) have been shown to successfully treat life-threatening arrhythmias in high-risk adults with hypertrophic cardiomyopathy (HCM).1 Children represent <1% of individuals with ICDs, and paediatric studies include few children with HCM. This study reports the experience with ICDs in children with HCM in a single referral centre.
Between 1993 and February 2006, 160 consecutively referred patients with HCM (age 
16 years) underwent clinical evaluation using 12-lead ECG, two-dimensional, M-mode and Doppler echocardiography, Holter monitoring and cardiopulmonary exercise testing using previously described methods.2 Risk markers for sudden cardiac death (SCD) were: (1) family history of SCD; (2) unexplained syncope; (3) abnormal blood pressure response during upright exercise; (4) non-sustained ventricular tachycardia; and (5) severe left ventricular hypertrophy (
30 mm).2 Patients with previous cardiac arrest or with 2 risk factors were considered for ICD implantation.2 All patients who underwent ICD implantation during this period were included in this study.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
Berul, C. I., Van Hare, G. F., Kertesz, N. J., Dubin, A. M., Cecchin, F., Collins, K. K., Cannon, B. C., Alexander, M. E., Triedman, J. K., Walsh, E. P., Friedman, R. A.
(2008). Results of a Multicenter Retrospective Implantable Cardioverter-Defibrillator Registry of Pediatric and Congenital Heart Disease Patients. J Am Coll Cardiol
51: 1685-1691
[Abstract] [Full Text] -
(2007). Lucina. Arch. Dis. Child.
92: 658-658
[Full Text]
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
hrt.2006.094730v1
93/3/372 most recent - Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Drugs: cardiovascular system
-
Hypertrophic cardiomyopathy
-
Interventional cardiology
-
Heart failure
-
Clinical diagnostic tests
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
