EDUCATION IN HEART
Congenital heart disease
Pulmonary regurgitation in congenital heart disease
Division of Cardiology, The Hospital for Sick Children, Toronto, Ontario, Canada
Correspondence to:
Correspondence to:
Professor Andrew N Redington
Division of Cardiology, The Hospital for Sick Children, 555, University Avenue, Toronto, Ontario, M5G 1X8, Canada; andrew.redington@sickkids.ca
| The first 150 words of the full text of this article appear below. |
The most important and best described clinical context for pulmonary regurgitation occurs in patients with repaired Tetralogy of Fallot. The first section deals briefly with pulmonary regurgitation in other situations; the remainder of the article deals with tetralogy of Fallot.
PULMONARY REGURGITATION IN CONDITIONS OTHER THAN TETRALOGY OF FALLOT
Isolated pulmonary regurgitation, in an otherwise normal heart, is well tolerated for decades. However, in a meta-analysis reported in the literature, 29% of patients had developed symptoms within 40 years.1 Many patients with a right ventricle to pulmonary artery conduit develop a mixture of obstruction and regurgitation across the conduit. However, some of these patients have regurgitation as the dominant lesion, and feature in pulmonary valve replacement series.2,3
Even valvar pulmonary stenosis treated surgically or by balloon dilatation can lead to significant pulmonary regurgitation requiring valve replacement. Fiftyseven per cent of patients had moderate to severe pulmonary regurgitation in a balloon dilatation series,w1 and in a surgical
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