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Heart 2008;94:1358-1360
Copyright © 2008 BMJ Publishing Group Ltd & British Cardiovascular Society

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Alistair Lindsay, Editor

The first 150 words of the full text of this article appear below.


INTERVENTIONAL CARDIOLOGY

TAPAS at 1 year: evidence for pre-PCI thrombus aspiration

The Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Myocardial Infarction (TAPAS) trial compared stenting for acute ST-elevation myocardial infarction with or without prior use of the Medtronic Export aspiration catheter. In the original trial, more than 1000 patients were randomised to bare metal stenting with or without thrombus aspiration (with predilatation being used only as necessary). The authors found that thrombus aspiration improved myocardial blush grade (17.1% vs 26.3%; p<0.001) and ST-segment resolution (56.6% vs 44.2%; p<0.001); would these benefits be sustained at 1 year?

At 12–month follow-up, cardiac death was 3.6% (19/535 patients) in the thrombus aspiration group and 6.7% (36/535) in the conventional PCI group (p = 0.020). Cardiac death or non-fatal reinfarction occurred in 5.6% (30/535) of patients in the thrombus aspiration group and 9.9% (53/536) of patients in the conventional PCI group (p = 0.009). These convincing results have led to many calling TAPAS a . . . [Full text of this article]


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