EDUCATION IN HEART

Myocardial disease

Neglected tropical cardiomyopathies: II. Endomyocardial fibrosis

Ana Olga Mocumbi^1,2, Sophie Yacoub¹, Magdi H Yacoub^1,2

¹ Imperial College, London, UK
² Maputo Heart Institute, Mozambique

Correspondence to:
Professor Magdi H Yacoub, FRS, Imperial College London, Heart Science Centre, Harefield, Middlesex, UB9 6JH, UK; m.yacoub@imperial.ac.uk

The first 150 words of the full text of this article appear below.

Endomyocardial fibrosis (EMF) was described as a distinct clinicopathological entity in 1948 in Uganda.^w1 Initially several terms were used to describe the disease. These included tropical endomyocardial disease, endocarditis parietalis fibroplastica, endocardial fibrosis, constrictive endocarditis and endocardial fibroelastose.

EPIDEMIOLOGY

EMF is thought to be the most common type of restrictive cardiomyopathy worldwide.¹ Although most studies have been reported from Uganda, Ivory Coast, Nigeria, Brazil and India, the disease has been occasionally encountered outside the tropics.² Geographic distribution of EMF is not uniform both in Africa and Asia.^{3 4} In the endemic areas of Africa, EMF is the second cause of admission for acquired cardiovascular disease in children and young adults, after rheumatic heart disease,^{5 w2} accounting for up to 20% of all causes of heart failure.

To date our knowledge of the prevalence of the disease is derived from hospital based studies with absence of data from systematic studies in the . . . [Full text of this article]

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