EDITORIALS
Does a stent cure hypertension?
Correspondence to:
Dr E N Oechslin, Adult Congenital Heart Disease Program, Peter Munk Cardiac Centre, University Health Network/Toronto General Hospital, 5 NUW – 519, 585 University Avenue, Toronto, ON M5G 2N2, Canada; erwin.oechslin@uhn.on.ca
| The first 150 words of the full text of this article appear below. |
Aortic coarctation, first described by Morgagni during an autopsy of a monk in 1760, is characterised by a circumscript narrowing in the region of the ligamentum arteriosum, at the level of the distal aortic arch/descending aorta, just at the origin of the left subclavian artery, in particular when diagnosed in adulthood. The natural history of aortic coarctation was dismal until 1944 when Crafoord and Nylin performed the first resection with end-to-end anastomosis in a human being.1 Natural survival of patients with unoperated aortic coarctation was 35 years on average and mortality at the age of 46 years was 75%. Premature morbidity and death in patient with unrepaired aortic coarctation are common owing to congestive heart failure (25.5%), rupture of the aorta (21%), endocarditis (18%) or intracranial haemorrhage (11.5%).2 This dismal prognosis of unoperated patients reflects the systemic nature of this congenital defect, in particular of the proximal, diseased aorta: cystic
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Heart 2008 94: 919-924.[Abstract] [Full Text] [PDF]
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